Vol. 1, No. 1 Contributors Pacific Northwest National Laboratories Editorial Staff Paula Yadvish Nathalie Fike Contacts "In making theories, always keep a window open so that you can throw one out if necessary." - Bela Schick, Pediatrician |
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Proteomics Resource News is a quarterly newsletter that features the work being done by the Administrative Center and Proteomics Research Centers. We will introduce the work being done under this project and supply updates through subsequent newsletters. We hope you will enjoy news regarding technologies and developments in the field of proteomics, progress on this project and relevant publications as well as activities of our members and internal groups. Subscribe to be notified of the next edition. Systems biology and proteomics at PNNL
Exploring how proteins and other chemicals work in concert to drive the functions of living organisms is one of the most exciting, important and growing areas in science today. Some of the leading work in this exploration, within the emerging fields of systems biology and proteomics, is taking place at the Department of Energy's Pacific Northwest National Laboratory. Systems biology at PNNL is focused on understanding complex interactions of gene, protein, and cellular components involved in cell signaling. Among PNNL's major contributions to this field are the proteomic resources developed and deployed in the William R. Wiley Environmental Molecular Sciences Laboratory, a DOE national scientific user facility located on the PNNL campus. EMSL also houses the NCRR Proteomics Research Resource for Integrative Biology. These resources are applied to a diverse range of studies, such as studies of how unique, radiation-resistant or metal-reducing organisms might be used in environmental cleanup processes, funded by the DOE's Office of Science. Collaborative studies with some of the world's leading biomedical research institutions promise to significantly add to our current understanding of how diseases originate and propagate in the body. These studies are supported in part through funding from the National Institutes of Health. Recent highlights of ongoing research include studies of human blood plasma (Plasma Proteomics Review and HUPO Discussion of the Field), other health related research (Hepatitis C virus, Human Cytomegalovirus, Lyme Disease, and Skeletal Muscle Channels), and advances in the field of microbial proteomics (Shewanella Hyphothetical Proteins, Shewanella Protein Complexes, Differential Deinococcus Proteomics, and Global Shewanella Proteomics). The possibilities for systems-level and proteomics studies are rapidly growing across every conceivable area of biological research. Enabled by interdisciplinary research coupled with excellent scientific resources, information can be collected at unprecedented levels. These efforts will lead to solutions for some of our nation's most pressing problems from health to energy production to biological-agent detection.
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| High throughput proteomics at PNNL Mass spectrometry is the premier tool for analyzing proteins under any set of conditions, and the William R. Wiley Environmental Molecular Sciences Laboratory at PNNL houses one of the world's most diverse, powerful and unique sets of mass spectrometers located under one roof. When combined with nanoscale ultra-high pressure capillary liquid chromatography (LC) separations, these ... continued on page 2 |
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Cambridge Healthtech Institute Cambridge Healthtech Institute (CHI) is renowned for its conferences. CHI holds approximately 60 conferences throughout the US and Europe and strives to develop quality programs that provide valuable new insights and competing points of view. "CHI events facilitate interaction with key decision-makers from leading pharmaceutical and biotech organizations."
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