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About the Protein Information Resource (PIR)
Georgetown University Medical Center (GUMC)

The Protein Information Resource (PIR), located at Georgetown University Medical Center (GUMC) and directed by Dr. Cathy Wu since 2001, is an integrated public bioinformatics resource that supports genomic and proteomic research and scientific studies.

PIR was established in 1984 by the National Biomedical Research Foundation (NBRF) as a resource to assist researchers in the identification and interpretation of protein sequence information. For four decades, PIR has provided many protein databases and analysis tools freely accessible to the scientific community, including the Protein Sequence Database (PSD), the first international database (see PIR-International). PIR maintains the Protein Sequence Database (PSD), an annotated protein database containing over 283 000 sequences covering the entire taxonomic range. In 2002, PIR along with its international partners, EBI (European Bioinformatics Institute) and SIB (Swiss Institute of Bioinformatics), were awarded a grant from NIH to create UniProt, a single worldwide database of protein sequence and function, by unifying the PIR-PSD, Swiss-Prot, and TrEMBL databases.

Today, PIR offers a wide variety of resources mainly oriented to assist the propagation and standarization of protein annotation, including PIRSF (Protein Family Classification System, iProClass (Integrated Protein Knowledge Base), and iProLINK (Literature, Information and Knowledge).