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2007 Meeting

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Biodefense Proteomics Research Centers
Fourth Programmatic Meeting
Salt Lake City Marriott Downlown
Salt Lake City, Utah
May 30-31, 2007

Meeting Objectives

  • Provide the Proteomics Research Centers (PRCs) with the opportunity to share their latest research in interactive forums
  • Broaden the outreach of this project by inviting participation from additional researchers from other National Institute of Allergy and Infectious Diseases (NIAID) projects and groups
  • Address administrative issues that benefit from face-to-face interactions between the Administrative Resource Center (RC) and the PRCs

Agenda
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Wednesday, May 30, 2007  
8:00 a.m. - 8:30 a.m. Registration/Breakfast
Mandatory Poster Set-up
Sign-up for One-on-One Sessions with RC staff
8:30 a.m. - 8:35 a.m. Welcoming Remarks
Mark Skolnick, Co-founder and Chief Scientific Officer, Myriad Genetics
8:35 a.m. - 8:40 a.m. Introductions
Members of the Scientific Working Group (SWG)
The Keynote Speaker
Bruno Sobral, Co-PI of the RC at Virginia Bioinformatics Institute/Virginia Tech University (VBI/VT)
8:40 a.m. - 9:30 a.m. Keynote Address: "Proteomics, Diagnostics and Biodefense"
Stephen Albert Johnston, Director, Center for Innovations in Medicine, The Biodesign Institute, Arizona State University
9:30 a.m. - 9:45 a.m. NIAID Project Officer Presentation: "State of the Biodefense Proteomics Research Centers "
Joseph Breen and Kimberly (JoJo) Stemple, Project Officers, NIAID, NIH
9:45 a.m. - 10:15 a.m. Resource Center Presentation: "Using the Web Resources "
Peter McGarvey, RC at Protein Information Resource/Georgetown University (PIR/GU)
Stephen Cammer, RC at VBI/VT
10:15 a.m. - 10:25 a.m. Break
10:25 a.m. - 12:30 p.m. Technological Developments in Proteomics
Moderator: Dick Smith, Pacific Northwest National Laboratories (PNNL)

Session Objectives
  • Examine the new technologies emerging from the PRCs
  • Discuss current and possible new uses of these technologies
  • Identify important biological questions with no current matching technologies

Introductory Remarks: Dick Smith – "Evolving Capabilities and Addressing Tougher Questions"
Representative Presentations:
RCE (Richard Willson, University of Houston, Western Regional Center for Excellence)
PRC (Peter Kuhn, Scripps)
Technology Highlights from other PRCs:
Caprion (Heather Butler)
Einstein (Ruth Angeletti)
Harvard (Josh LaBaer)
Michigan - Yates Lab (Emily Chen)
Discussion and Questions: Audience participation and questions
Concluding Remarks: Dick Smith

12:30 p.m. - 1:30 p.m. Lunch
1:30 p.m. - 3:30 p.m. Intracellular Pathogen Session
Co-Moderators: Eustache Paramithiotis (Caprion) and Phil Hanna (University of Michigan)

Session Objectives
  • Highlight intracellular strategies used by pathogens that contribute to their survival and/or disease pathologies
  • Describe patterns of host cell responses and/or deficiencies induced upon challenge by intracellular pathogens
  • Utilize audience expertise of how current PRC approaches can best be applied to examine these phenomena, and develop themes for new experiments that will lead to advances in this important area

Introductory Remarks: Eustache Paramithiotis
PRC Participants:
Albert Einstein - T. gondii/C. parvum (Louis Weiss)
Michigan - B. anthracis (Nick Bergman)
Myriad - B. anthracis (Ken Bradley)
PNNL - Salmonella sp. (Fred Heffron)
Discussion and Questions:
Audience participation and questions
Concluding Remarks: Phil Hanna

3:30 p.m. - 3:45 p.m. Break
3:45 p.m. - 3:50 p.m. Program Deliverables: "Strategy for Monitoring Deliverables: A Partnership"
JoJo Stemple
3:50 p.m. - 4:00 p.m. Biodefense and Emerging Infections Research Resource Repository (BEI): New Registration Procedures
Rebecca Bradford
4:00 p.m. - 6:00 p.m. Poster Presentations
4:30 p.m. - 6:00 p.m.

Additional Activities

  • BEI Registration: The BEI representative will assist investigators with registration, material submission, and any questions regarding interactions with BEI
  • PRC-RC One-on-One Session I: First of two sessions set aside for the PRCs and representatives from the RC to sit face-to-face to exchange ideas and address issues of communication, data and specimen submission, and/or other items ofmutual importance
6:30 p.m. - 8:30 p.m. Project-wide Dinner at Bambara
   
Thursday, May 31, 2007  
8:00 a.m. - 8:30 a.m. Breakfast and Poster Viewing
8:30 a.m. - 10:30 a.m Viral Pathogen Session
Moderator: Michael Buchmeier (Scripps)

Session Objectives
  • Accelerate and extend understanding of host-pathogen relationships through optimal use of new information
  • Integration of structural, functional and host response data: Identify steps for improvement
  • Examine measures of success:
  • Will the work of this program lead to advances in diagnostics and therapies that are applicable in an emerging infection outbreak or intentional release event?
  • How can the work of this program be integrated into mainstream medicine?

Introductory Remarks: Michael Buchmeier
Main Presentation: Poxvirus-Host Interactions: 'Where Next?"
Grant McFadden, Director, Emerging Pathogens Initiative, College of Medicine
University of Florida (Myriad Collaborator)
PRC Presentations:
PNNL (Scott Wong)
Scripps (Peter Kuhn)
Discussion and Questions: Audience participation and questions
Concluding Remarks: Michael Buchmeier

10:30 a.m. - 10:45 a.m Break
10:45 a.m. - 11:45 a.m Poster Presentations Session II

Additional Activities
  • BEI Registration: The BEI representative will assist investigators with registration, material submission, and any questions regarding interactions with BEI
  • PRC-AC One-on-One Session II: Second of two sessions set aside for the PRCs and representatives from the AC to sit face-to-face to exchange ideas and address issues of communication, data and specimen submission, and/or other items ofmutual importance
11:45 a.m. - 12:00 noon Summary and Wrap-up
Cathy Wu (PIR/GU)
12:00 noon- 1:00 p.m. Lunch
12:45 p.m. - 2:30 p.m. Scientific Working Group Meeting - By Invitation Only - Agenda

Questions regarding this meeting should be directed to: or

 


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