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The Scripps Research Institute
Back to Biodefense Proteomics Catalog
Objective:
Focus on specific targets from viruses in the NIAID list of category A-C pathogens and those causing emerging and re-emerging diseases generating structures that can then be the basis for further therapeutic and diagnostic developments. Studies of viral proteins and their complexes represent a relatively unexplored area in structural biology.
| pp1a | pp1b | |||||||||||||||
| nsp1 | nsp2 | nsp3 | nsp4 | nsp5 | nsp6 | nsp7 | nsp8 | nsp9 | nsp10 | nsp11 | nsp12 | nsp13 | nsp14 | nsp15 | nsp16 | |
| leader | p65 | multi- domain |
3-TM | 3CL- Pro |
7-TM | 4- Helix |
Golf Club |
RNA Binding |
Zn- finger |
? | RdRp | Heli- case |
ExoN | NendoU | Methyl- Transfer- ase |
|
| nsp3 (expanded) | ||||||||||||||||
| UB1 | AC | ADRP | SUDN | SUDC | UB2 | PLP2 | RNABD | UNK | TM1 | TM2 | ZF | TM3 | TM4 | Y | ||
| sars2 | sars3a | sars4 | sars5 | sars6 | sars7a | sars8 | sars9a | |||||||||
| sars3b | sars7b | sars9b | sars14 | |||||||||||||
| Spike | E | M | 1-TM | Ig-fold | 1-TM | N | lipid- binding |
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| Replicate Proteins | Structural Proteins | Accessory Proteins | FSPS NMR Structure | FSPS Crystal Structure | Structures by Other Groups |
View an in-depth summary of the SARS-CoV proteome.
Summary view of available info:
*mouse slowly over column headers for more information
| PRC | Organism | Data Type | Master Protein Directory | Data Sets | SOPs | Pathogen Specific Publications |
Reagents | Complete Predicted Proteome |
| Scripps Research Institute |
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Key to Catalog Links
| PRC = view information about the Proteomics Research Centers Organism = view detailed information about the selected organism Master Protein Directory = view all identified pathogen and host proteins Pathogen or Host Data Sets = view data sets/experimental details for pathogen and host |
SOPs = view or download related experiment Standard Operating Procedures Pathogen Specific Publications = view abstracts, manuscripts and/or publications Reagents = request reagents by ID from BEI, PFGRC or PlasmID Complete Predicted Proteome= view complete predicted proteomes |
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