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Cryptosporidium parvum
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Description

Cryptosporidium is taxonomically classified as a Sporozoa, since its oocyst releases four sporozoites (its motile infectious agents) upon excystation. However, it differs from related parasites such as Toxoplasma by its monoxenous life cycle — completing its entire cycle within a single host (Flanigan and Soave, 1993).
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Significance in Biodefense Proteomics

The concern is an attack on water supplies to major cities. The cells in the sporocyst stage are resistant to most chemical disinfectants including chlorine found in both drinking and swimming pool water, but are susceptible to drying and the ultraviolet portion of sunlight. C. parvum has a low ID50 — Less than 10 organisms and, presumably, one organism can initiate an infection.

 

Photomicrograph reveals the morphologic details of Crystosporidium parvum oocysts

Micrograph of a direct fecal smear is stained to detect Crystosporidium parvum, an intracellular protozoan parasite
from Public Health Image Library (PHIL)

*mouse slowly over column headers for more information

Organism PRC Data Type Pathogen
or Host
Data Sets
SOPs Master Protein Directory Pathogen Specific
Publications
Reagents Complete Predicted Proteome
Cryptosporidium parvum
Einstein Biodefense Proteomic Research Center
Technology
Mass spectrometry
1
2
-
4
-
634
-
Antibodies
-


Key to Catalog Links

Organism = view detailed information about the selected organism
PRC = view information about the Proteomics Research Centers
Pathogen or Host Data Sets = view data sets/experimental details for pathogen and host
SOPs = view or download related experiment Standard Operating Procedures

Master Protein Directory = view all identified pathogen and host proteins
Pathogen Specific Publications = view abstracts, manuscripts and/or publications
Reagents = request reagents by ID from BEI, PFGRC or PlasmID
Complete Predicted Proteome= view complete predicted proteomes


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