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Francisella tularensis
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Description Francisella tularensis is a small, weakly staining, gram-negative cocco-bacillus, 0.2 by 0.2 to 0.7 um in size. It is non-motile, with a thick capsule, and is a facultative intracellular parasite: it undergoes phagocytosis but evades intracellular killing. Significance in Biodefense Proteomics Francisella tularensis, the causative agent of tularemia, is considered a potential bioterrorism agent. It was originally isolated by McCoy and Chapin in 1911 in Tulare County, CA, and named Bacterium tularence. Dr. Edward Francis, in 1921 linked the bacterium to several syndromes such as deer fly fever, rabbit fever, rancher's fever, etc. and the organism was later re-named Francisella tularensis in his honor. USAMRIID (U.S. Army Medical Research Institute of Infectious Diseases ) developed a vaccine against tularemia for at risk and military personnel in the 1960's using a live, attenuated strain of F. holarctica, now commonly called the LVS strain. The LVS strain was originally isolated in the former Soviet Union from a water rat and transferred from Moscow, Russia to the USAMRIID in 1956. |
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| Organism | PRC | Data Type | Pathogen or Host Data Sets |
SOPs | Master Protein Directory | Pathogen Specific Publications |
Reagents | Complete Predicted Proteome |
| Francisella tularensis |
| 4631 |
Key to Catalog Links
| Organism = view detailed information about the selected organism PRC = view information about the Proteomics Research Centers Pathogen or Host Data Sets = view data sets/experimental details for pathogen and host SOPs = view or download related experiment Standard Operating Procedures |
Master Protein Directory = view all identified pathogen and host proteins Pathogen Specific Publications = view abstracts, manuscripts and/or publications Reagents = request reagents by ID from BEI, PFGRC or PlasmID Complete Predicted Proteome= view complete predicted proteomes |
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