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Salmonella typhimurium
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Description Salmonella is a Gram-negative bacterium, a cylindrical rod of size about 2 microns by 0.5 microns, thus much smaller than the cells of higher organisms such as humans. In culture, the bacterium will grow on artificial media to form colonies. Salmonella typhimurium multiplies in the gastrointestinal tract of many animal species where it usually causes no disease, but in humans its growth causes gastroenteritis. Six to 48 hours after ingestion of contaminated water or food (usually poultry or beef), illness may begin with nausea and vomiting, often followed by diarrhea. In healthy adults the disease is usually self-limiting with good medical care, but it is more serious in the young, the old, and those with underlying medical conditions; the case-fatality ratio can be as high as 5-10% in nurseries and nursing homes. Isolations of Salmonella causing gastroenteritis in humans have increased in recent years in developed countries, primarily because modern methods of animal husbandry, food preparation, and distribution encourage the spread of Salmonella. Significance in Biodefense Proteomics |
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Typhimurium causes a systemic disease in mice that is similar to typhoid in humans. Thus typhimurium has been extensively used as a model for typhoid. |
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*mouse slowly over column headers for more information
| Organism | PRC | Data Type | Pathogen or Host Data Sets |
SOPs | Master Protein Directory | Pathogen Specific Publications |
Reagents | Complete Predicted Proteome |
| Salmonella typhimurium |
| 4532 |
Key to Catalog Links
| Organism = view detailed information about the selected organism PRC = view information about the Proteomics Research Centers Pathogen or Host Data Sets = view data sets/experimental details for pathogen and host SOPs = view or download related experiment Standard Operating Procedures |
Master Protein Directory = view all identified pathogen and host proteins Pathogen Specific Publications = view abstracts, manuscripts and/or publications Reagents = request reagents by ID from BEI, PFGRC or PlasmID Complete Predicted Proteome= view complete predicted proteomes |
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